Seeking a Postdoctoral Researcher (IMS109-2002)(Laboratory for Cellular Epigenomics) 1. Researcher/Postdoc level

RIKEN(The Institute of Physical and Chemical Research)

勤務地
Kanto district - Kanagawa 
給与
非掲載

こんな仕事です

機関名
Institution RIKEN(The Institute of Physical and Chemical Research) 求人内容
Content of job information [Laboratory]
Laboratory for Cellular Epigenomics
RIKEN Center for Integrative Medical Sciences
(Team Leader: Aki Minoda)
[Research Field]
Our mission is to understand ageing from a molecular point of view, in particular to understand what kind of epigenomic/chromatin changes take place during ageing, the findings of which we hope will eventually result in `healthy longevity', towards a society where people can live healthier longer. This is increasingly important in the world where the trend is people are living longer but the number of young people and caretakers are not catching up.
Although every single cell in our body carries the same genomic information encoded by the DNA (the genome), there are at least 300 different cell types in a human body as we know today, which carry out different functions as well as taking different shapes. These differences are due to each one of them carrying a different epigenome, which include DNA methylation and histone modifications that are essentially regulating transcriptional states. In other words, one can also say a cell type is defined by its epigenome and is necessary to carry out cell type-specific function. When epigenome of a cell is compromised in any way, cell type-specific functions may be compromised, which may result in a loss of function at the organ level. Consistently, many disease cells have been shown to have altered epigenomes. We aim to understand how the epigenomes and therefore the transcriptomes are altered during ageing or in ageing mutant models.
For more information, please refer to:
・Laboratory for Cellular Epigenomics
・Laboratory for Cellular Epigenomics | RIKEN Center for Integrative Medical Sciences
[Job title and Job description]
Position available:
One opening for a Postdoctoral Researcher
Job descriptions:
The goal of this project is to characterise the effect of microbiota on intestines during ageing. The selected candidate will be involved in analysing RNA-seq and DNA methylation datasets mainly, as well as microbiome data, which were obtained from intestine tissues of different aged SPF and germ-free mice. This project is in collaboration with another lab and the candidate is expected to communicate well with the collaborating lab members.
*Postdoctoral Researcher: Carries out research and other work in accordance with team research themes under the mentorship and training of supervisors.
[Work location]
RIKEN Center for Integrative Medical Sciences
1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama-shi, Kanagawa 230-0045 Japan
[Start of Employment]
January 1, 2021 (negotiable)
[Keyword]
Epigenome,Transcriptome,Chromatin,Ageing,Aging,
Single cell analysis,Gene regulation
研究分野
Research field 1. 大分類 Biology
小分類 All Biology
勤務形態
Employment status Full-time(Nontenured) 応募資格
Qualifications 1.Should have an experience and knowledge of bioinformatics analysis.
2.Must be a team player who has proactive and constructive attitude.
3.Must have excellent communication skills and be able to engage in research in a coordinated manner in order to complete the assigned tasks with the members of mixed nationalities.
4.Comfortable with English as a professional language for scientific discussion and publication (Japanese language skills are not required).
5.PhD holder in fields indicated under [Job description] with less than three years.
待遇
Compensation For details about "Salary and benefits", please refer to the above "Job posting URL".

募集要項

  • 応募条件
    1.Should have an experience and knowledge of bioinformatics analysis.
    2.Must be a team player who has proactive and constructive attitude.
    3.Must have excellent communication skills and be able to engage in research in a coordinated manner in order to complete the assigned tasks with the members of mixed nationalities.
    4.Comfortable with English as a professional language for scientific discussion and publication (Japanese language skills are not required).
    5.PhD holder in fields indicated under [Job description] with less than three years.
  • 勤務地
    Kanto district - Kanagawa 
  • 給与
    非掲載

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